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La propriété est composée de 16 chambres. Folic acid 48 Folic acid forms part of the B complex of vitamins. Vitamin H 61 Vitamin H biotin , a water-soluble vitamin, assists in the utilisation of protein, folic acid and vitamin B12 the latter is not the subject of the present procedure. Most Popular; Videos 3; Backdrops 3; Posters Omega laen S.

The European market for calpan in was worth some ECU 35 million. Vitamin B6 44 Vitamin B6 pyridoxine serves as a coenzyme for many enzymes involved in the metabolism of amino acids. It plays a significant role in the metabolism of proteins, carbohydrates and fats. Adult ruminants are usually self-sufficient in vitamin B6, but young animals require supplements while growing. Vitamin B6 has a variety of uses in animal and human nutrition and in the pharmaceuticals industry.

It is currently worth about EUR 11 million.

Folic acid 48 Folic acid forms part of the B complex of vitamins. The name is applied to a whole group of compounds also known as folates or folacin. It plays an important role in the metabolism of DNA and RNA, the carriers of genetic information in all living organisms. Folic acid reduces the risk of neural tube birth deformities in humans if consumed in adequate quantities by the expectant mother during pregnancy.

In humans folic acid deficiency can also result in anaemia. Folic acid deficiency in animals causes anaemia and, in poultry, reduced laying performance and poor feathering. Roche produces folic acid mainly for incorporation in its pre-mixes. The Japanese folic acid producers do not produce pre-mix, with the exception of a Takeda subsidiary which supplies the product locally in Japan.

Until then Roche did not produce folic acid, but obtained its requirements from Takeda.

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Vitamin C 52 Vitamin C ascorbic acid is a water-soluble vitamin which is used mainly in the human nutrition and pharmaceutical industries. It is required for the production in the living organism of collagen, the intercellular substance which gives structure to muscles, bone, vascular tissue and cartilage.

Deficiency causes scurvy weakening of the tissues and intercapillary bleeding. Humans are dependent upon vitamin C supply in the diet. Most food producing animals but not fish can synthesise vitamin C themselves, but may require a supplement to natural production. Vitamin C is also used as an antioxidant to protect the colour or aroma of foodstuffs.

Vitamin D3 56 Vitamin D3, a fat-soluble vitamin like vitamins A and E, is sold either in straight form or more often in a blend with vitamin A known as "AD3". It also plays a role in the proper functioning of muscles, nerves, blood clotting and cell growth. Deficiency leads to rickets in children and osteomalacia in adults; in animals, it leads to reduced growth and leg disorders and, in poultry, thin egg shells. Solvay Pharmaceuticals produced about half the world requirement of vitamin D3 in the early s but its share of the "third party" market was much smaller.

Solvay does not produce blends or pre-mixes: it supplies the straight product to other vitamin producers like Rhône-Poulenc, vitamin formulators which buy in concentrated form, distributors and resellers and to pre-mixers and feed producers. The producers use the D feed grade form as the market grade.

The price for feed grade vitamin D3 in Europe in was subject to considerable variations between the different countries. Vitamin H 61 Vitamin H biotina water-soluble vitamin, assists in avis fat burner nutrrimuscle utilisation of protein, folic acid and vitamin B12 the latter is not the subject of the present procedure.

Biotin is produced through chemical synthesis involving some 20 different processes Tanabe is avis fat burner nutrrimuscle a fermentation process but it is not yet in commercial use. It is sold in pure and diluted form. Pharmaceutical grade is marketed in pure form. Lonza ceased production in Beta-carotene and carotinoids 65 Strictly speaking these products are not vitamins.

Beta-carotene is a pro-vitamin of vitamin A found naturally in plants; when ingested it is converted by the living organism into vitamin A.

The vast majority of beta-carotene supplies are purchased by the food and also by the pharmaceutical industry. Carotinoids are generally classified by the colour they produce when ingested by animals. Canthaxanthin and citranaxanthin are used to produce a red or golden colour and are referred to as the red carotinoids. The Community market for canthaxanthin, the principal carotinoid product, is in the region of EUR 50 million annually.

However, there are several indications that point to worldwide markets for each of the vitamin products. This is demonstrated by the fact that a number of companies based in Japan traded in Europe. In addition, all the main companies sold the various products in the main regional markets America, Asia, Europe. The third European producer is Merck in Germany. Roche's B-complex production is at Grenzach in Germany.

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Roche 76 Hoffmann-La Roche AG is one of the world's largest research-based pharmaceutical and healthcare groups. The company's headquarters are in Basel, Switzerland.

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It has manufacturing facilities in a number of Member States. Vitamin sales worldwide totalled CHF 1,96 billion and carotinoids also the subject of this procedure, although not strictly speaking vitamins CHF million. Roche is the largest manufacturer of vitamins both worldwide and in Europe. The company started producing vitamin C by chemical synthesis in and expanded its activities to produce the whole range of vitamins.

Its range of production is the widest of all the vitamin producers. Roche also supplies other vitamin products bought in from other manufacturers so that it markets the full range of vitamins for all possible uses: animal feed, food, pharmaceutical and cosmetics 6. Other products of the Division include feed enzymes, emulsifiers, citric acid and fatty acids.

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Its operations cover oil and gas, bulk chemicals, plastics, high performance chemical products, plant-protection products and pharmaceuticals. The health and nutrition segment of BASF includes the fine chemicals division which in turn includes vitamins for human and animal nutrition.

BASF ceased its own production of vitamin B1 in but continued to act as a major supplier selling product bought in from other producers. It also purchases for resale the major part of the biotin vitamin H output of another German producer, Merck.

Rhône-Poulenc now Aventis 88 Rhône-Poulenc SA, whose corporate headquarters were in Courbevoie, France, was an international company involved in the research, development, production and marketing of organic and inorganic intermediate chemicals, speciality chemicals, fibres, plastics, pharmaceuticals and agricultural chemicals.

The next step was to be the complete merger of the two parent companies. Aventis is led by a board of management of four members and an executive committee which consists of the four board members and five other senior executives.

The new group is divided into two business areas, Aventis Pharma and Aventis Agriculture. Aventis Agriculture comprises the crop science, plant biotechnology, animal nutrition and animal health businesses.

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The chief executive officer of Aventis Agriculture, who was formerly the president of Rhône-Poulenc's plant and animal health division, is also a member of the executive committee of Aventis. The new company is headquartered in Strasbourg.

Its name has been changed to "Aventis Animal Nutrition". RPAN's main feed additive products are vitamins A and E used in poultry and pig feed and methionine, an essential amino-acid used mainly for poultry feed and not the subject of the present procedure.

Vitamins A and E are produced in Commentry, France. Lonza 98 Lonza AG is a Swiss chemical producer founded in In it was acquired by what was then Alusuisse AG, as an independently managed subsidiary and became part of the Alusuisse Lonza Group Algroup. In Algroup demerged its chemicals and energy activities from the rest of the group in anticipation of the proposed merger of its aluminium and specialty packaging activities with those of Pechiney and Alcan Up to it was part of the Avis fat burner nutrrimuscle industrial group.

It produces pharmaceutical drugs for human use. The only vitamin it produces and sells is vitamin D3. It is established as the operating subsidiary of E. Merck oHG. Merck oHG now acts purely as a holding company.

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Merck's relevant products for the purposes of this procedure are vitamins C and H biotin. Daiichi Daiichi Pharmaceutical Co. Ltd of Tokyo, Japan, was founded in and produces a wide range of ethical pharmaceuticals, over-the-counter health products and veterinary products. Daiichi's relevant vitamin production is in vitamins B5 calpan and B6. Eisai Eisai Co.

Ltd of Tokyo is a leading Japanese pharmaceutical and drug manufacturer specializing in ethical drugs. The only relevant product for present purposes is folic acid. Sumitomo Sumitomo Chemical Company Ltd of Osaka and Tokyo is one of Japan's largest chemical manufacturers, with a product range including basic chemicals, petrochemicals, fine chemicals, agricultural chemicals and pharmaceuticals.

The relevant product for present purposes is folic acid.

VITAMINS 3 Vitamins are a group of micronutrients of various types of organic compounds required in small amounts in human and animal diet for normal growth, development and maintenance of life.

Takeda Takeda Chemical Industries Ltd, also of Osaka, and incorporated inis engaged in industrial chemicals, drugs, cosmetics and healthcare products and is a leading manufacturer of pharmaceuticals operating on a global basis; it is the principal vitamin producer in Japan and also one of the main producers of bulk vitamins worldwide. Tanabe Tanabe Seiyaku Co. Ltd of Osaka is one of the leading pharmaceutical producers in Japan.

Tanabe buys in other bulk vitamins from other producers, including Roche vitamins B1 and C and either uses them in its downstream production or resells them as a trader. The second column shows data for the worldwide turnover in the vitamin product concerned in the last complete calendar year of the infringement and, in brackets, the range of the company's market share in the worldwide market concerned during the time period of the infringement.

The third column shows the same information as that of column two but in relation to the EEA-wide vitamin product market instead of the worldwide market.

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All of these figures are necessarily approximate. They informed the Commission of their intention to cooperate with any investigations, but without at the time providing any statement or documentary evidence. These statements only covered the vitamin products which were the subject of the prosecutions in the United States of America.

As regards pre-mixes, the producers claimed that while there had been sporadic discussions on pre-mix in Europe, there had never been any effective agreements for this format, since most sales were made as "straights" The requests did not relate to all the products in respect of which collusion on their part was suspected Takeda claimed it had already prepared the file before receipt of the Article 11 request.

It provided a reply to the request for information on 18 and 20 October concerning vitamins B1 and B6. It also provided further documents on folic acid, and on 10 January provided a response to a request for information in relation to folic acid, sent on 15 November On 22 November it provided certain avis fat burner nutrrimuscle documents regarding the arrangements in that product.

The Commission provided a full copy of all accessible and partially accessible documents in its file of the case, including non-confidential versions of partially accessible documents, in the CD-ROM which was provided to all addressees of the statement of objections.

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A descriptive list of the content of the non-accessible documents was established and provided to the same addressees. At the Oral Hearing the undertakings were also given the opportunity to comment on the written replies of the other parties which had been made available to them earlier.

Certain individuals were also charged with criminal violations of the Sherman Act. The vitamins and time periods concerned were as follows: - vitamins A and E: from January to February- vitamin B2: from January to at least Fall- vitamin B5: January to at least December- vitamin C: from January to at least Fall- beta-carotene: from January to at least Decemberand - vitamin pre-mixes: from January to at least December Two of the most senior executives of Roche, Messrs[ The origin and basic scheme of the cartels The European producers state that prices for both vitamin A and E actually fell significantly during the late s as a result of competition.

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The "dramatic" fall in price in vitamin E is attributed by Roche to the "price offensive" of Eisai in for vitamin A, Roche blames dolphini fitness kaalulangus aggressive pricing policy of Rhône-Poulenc. The meeting lasted two days.

Eisai did not attend; Roche says the idea was to bring Eisai in at a second stage. Market shares were frozen at levels; as the market expanded, each company could increase its sales only in accordance with its agreed quota and in line with market growth and not at the expense of a competitor. The maxim "price before volume" was accepted as the underlying principle of the cartel. Specific pricing levels were also discussed. For each avis fat burner nutrrimuscle, including Europe, the market share quotas were further broken down country by country, so that the total of the allocations corresponded with the regional share assigned and the regional shares added up to the world quotas.

Structure and participants Structure of regular meetings As the implementation of the cartel developed, a complex structure of regular meetings evolved. There were four levels.

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